Work

Lipophilicity is a critical parameter that dominates the efficacy of metalloporphyrins in blocking the development of morphine antinociceptive tolerance through peroxynitrite-mediated pathways

Year: 2008

Type: article

Source: Free Radical Biology and Medicine

DOI: 10.1016/j.freeradbiomed.2008.09.037

Authors: Ines Batinić-Haberle, Michael M. Ndengele, Salvatore Cuzzocrea, Júlio S. Rebouças, Ivan Spasojević, Daniela Salvemini

Institutions: Duke University, Duke Medical Center, Saint Louis University, University of Messina, Centro Neurolesi Bonino Pulejo

Language: English

Topic: Pain Mechanisms and Treatments

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Università degli Studi di Messina, National Institutes of Health, National Institute on Drug Abuse, National Cancer Institute, National Institute of Allergy and Infectious Diseases

Awards: G1174881085, G1407413457, G1700414332, Role of peroxynitrite in morphine hyperalgesia and tolerance, G3394654207, Centers for Medical Countermeasures Against Radiation, Cancer Center Support Grant (CCSG)

OpenAlex ID: W2069208059

FWCI: 4.217

Cites: 86

Cited by: 47

Related to: 10