A chemical and histochemical study of enzymes dephosphorylating adenosine phosphate esters in the epididymis of normal, castrated, and testosterone propionate treated castrated mice
Year: 1959
Type: article
Abstract: TWENTY E'IGUXFSStudy of the distribution of acid and alkaline phosphatases in the epididymis of the mouse has shown these enzymes to have widely divergent localizations.Alkaline phosphatase (Allen and Slater, '57) was distributed primarily in the apical portions of the epithelial cells of the head segments of the epididymal canal.Special cells in the head segments and all epithelial cells of the body and tail segments of the canal showed no alkaline phosphatase activity.Acid phosphatase (Allen and Slater, '58) was localized in the Golgi area of epithelial cells in the head segments of the duct.Special cells in the head, body and tail of the epididymal canal showed high levels of activity generally distributed in their cytoplasm, These results indicated that the cells of the epididymal canal were heterogeneous in their enzymatic composition.Since this heterogeneity existed f o r phosphatases of broad substrate specificity it appeared to us that phosphatases of more restricted substrate characteristics might show further interesting distributional patterns in this tissue.Enzymes dephosphorylating phosphate esters of adenosine form one such group of substrate-restricted enzymes.This paper deals
Source: American Journal of Anatomy
Authors: John M. Allen, Judith J. Slater
Institutions: University of Michigan, United States Public Health Service
Language: English
Subfield: Reproductive Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2069861442