Work

Cloning and expression of chicken erythrocyte transglutaminase.

Year: 1992

Type: article

Abstract: We report the sequences of cDNAs encoding chicken erythrocyte transglutaminase (EC 2.3.2.13). The complete mRNA consists of 3345/3349 nucleotides and predicts a single open reading frame. Nine peptide sequences derived from partial digests of the isolated protein agreed with the corresponding translation of the open reading frame. Approximately 60% identities between the avian protein and three related mammalian enzymes were found. Chicken erythrocyte transglutaminase mRNA is most abundant in red blood cells and kidney, and it accumulates during erythroid cell differentiation.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.89.20.9804

Authors: N Weraarchakul-Boonmark, J M Jeong, S N Murthy, J D Engel, L Lorand

Institution: Northwestern University

Language: English

Topic: Blood properties and coagulation

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

Open Access status: green

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute

Awards: G372560590, G5055061352, BLOOD CELL DEVELOPMENT AND FUNCTION, BLOOD, MUSCLE AND PROSTATE CHEMISTRY