Work

Analysis of the cercosporin polyketide synthase CTB1 reveals a new fungal thioesterase function

Year: 2012

Type: article

Abstract: The polyketide synthase CTB1 is demonstrated to catalyze pyrone formation thereby expanding the known biosynthetic repertoire of thioesterase domains in iterative, non-reducing polyketide synthases.

Source: Chemical Communications

DOI: 10.1039/c2cc36010a

Authors: Adam G. Newman, Anna L. Vagstad, Katherine Belecki, Jonathan R. Scheerer, Craig A. Townsend

Institutions: Johns Hopkins University, William & Mary

Language: English

Topic: Microbial Natural Products and Biosynthesis

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

Open Access status: green

Funders: National Institute of General Medical Sciences, National Institute of Environmental Health Sciences

Awards: G212905542, The Chemistry-Biology Interface Program at Johns Hopkins University, Iterative Polyketide Synthase Function, Structure and Pathways

OpenAlex ID: W2070071623

FWCI: 2.353

Cites: 24

Cited by: 53

Related to: 10