Work

Conus Peptides: Biodiversity-based Discovery and Exogenomics

Year: 2006

Type: article

Abstract: The venoms of the ∼700 species of predatory cone snails (genus Conus) are being systematically characterized. Each Conus species contains 100–200 small, highly structured venom peptides (colloquially known as conotoxins), which are synthesized and secreted in a venom duct (for overviews, see Refs. 1–3). The biomedical potential of these small venom peptides is now well established; recent developments are summarized below. Additionally, the genetic basis and biological rationale for Conus peptide diversity is addressed.

Source: Journal of Biological Chemistry

DOI: 10.1016/s0021-9258(19)84029-2

Author: Baldomero M. Olivera

Institution: University of Utah

Language: English

Topic: Venomous Animal Envenomation and Studies

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $3,430

Funder: National Institute of General Medical Sciences