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Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells

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Year: 2011
Type: article
Study design: Observational Study
Source: Nature Medicine
DOI: 10.1038/nm.2430
Authors: Barthelemy Diouf, Qing Cheng, Natalia F Krynetskaia, Wenjian Yang, Meyling Cheok, Deqing Pei, Yiping Fan, Cheng Cheng, Evgeny Y Krynetskiy, Hui Geng, Siying Chen, William E Thierfelder, Charles G Mullighan, James R Downing, Peggy Hsieh, Ching-Hon Pui, Mary V Relling, William E Evans
Institutions: St. Jude Children's Research Hospital, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases
Language: English

Topic: DNA Repair Mechanisms
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences
Awards: PAAR4Kids-Pharmacogenomics of Anticancer Agents Research in Children, G609259107, PHARMACOGENOMICS OF CHILDHOOD LEUKEMIA (ALL), Cancer Center Support Grant (CCSG)
OpenAlex ID: W2070569107
FWCI: 4.129
Cites: 36
Cited by: 129
Related to: 10
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