Work

CDK6, a new target in MLL-driven leukemia

Year: 2014

Type: article

Abstract: In this issue of Blood, Placke et al identify the cell-cycle regulator CDK6 as a promising new target in mixed lineage leukemia (MLL)-rearranged acute myeloid leukemia (AML) and show that its downregulation or pharmacological inhibition leads to growth inhibition and differentiation of MLL-driven leukemic cells.

Source: Blood

DOI: 10.1182/blood-2014-05-572917

Authors: Iléana Antony-Debré, Ulrich Steidl

Institution: Albert Einstein College of Medicine

Language: English

Topic: Acute Lymphoblastic Leukemia research

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2070861847