Work

Synthesis of a Homologous Series of Side-Chain-Extended Orthogonally Protected Aminooxy-Containing Amino Acids

Year: 2008

Type: article

Abstract: Practical methodology is reported for the synthesis of a homologous series of side chain extended amino acids containing aminooxy functionality bearing orthogonal protection suitable for Fmoc peptide synthesis. These reagents may be useful for the preparation of libraries containing fragments joined by peptide linkers.

Source: Synthesis

DOI: 10.1055/s-2008-1078600

Authors: Terrence Burke Jr., Fa Liu, Joshua Thomas

Institutions: National Institutes of Health, Frederick National Laboratory for Cancer Research, Center for Cancer Research

Language: English

Topic: Chemical Synthesis and Analysis

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funder: National Institutes of Health

Awards: G6374948078, G9000330576