Work

A sensitive high-throughput method to detect activating mutations of Jak2 in peripheral-blood samples

Year: 2006

Type: article

Abstract: An activating mutation of the Jak2 tyrosine kinase (V617F) is commonly detected in polycythemia vera (65%-97%),[1][1]-[6][2] essential thrombocythemia (23%-57%),[1][1],[2][3],[4][4]-[6][2] and idiopathic myelofibrosis (35%-57%)[1][1],[2][3],[4][4]-[6][2] as well as at low percentages in other

Source: Blood

DOI: 10.1182/blood-2005-07-2899