Work

Room-Temperature C–H Arylation: Merger of Pd-Catalyzed C–H Functionalization and Visible-Light Photocatalysis

Year: 2011

Type: article

Abstract: This communication describes the development of a room-temperature ligand-directed C-H arylation reaction using aryldiazonium salts. This was achieved by the successful merger of palladium-catalyzed C-H functionalization and visible-light photoredox catalysis. The new method is general for a variety of directing groups and tolerates many common functional groups.

Source: Journal of the American Chemical Society

DOI: 10.1021/ja208068w

Authors: Dipannita Kalyani, Kate B. McMurtrey, Sharon R. Neufeldt, Melanie S. Sanford

Institution: University of Michigan

Language: English

Topic: Catalytic C–H Functionalization Methods

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute of General Medical Sciences

Awards: G1731921186, C-H Bond Functionalization in Organic Synthesis