Year: 2008
Type: article
Abstract: stalled replication forks; how FA core complex loading leads to DNA repair also remains to be determined.Nevertheless, the study by Kim and colleagues unequivocally shows that FANCM plays a regulatory role in the FA pathway, and provides evidence that the dysregulated loading of the FA core complex to chromatin accounts, at least partially, for the characteristic phenotype of FA cells.Conflict-of-interest disclosure: The authors declare no competing financial interests.■
Source: Blood
Authors: Steven Z. Pavletic, Daniel H. Fowler
Institution: National Cancer Institute
Language: English
Topic: T-cell and B-cell Immunology
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W2071456738