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Understanding the Molecular Basis of Toxin Promiscuity: The Analgesic Sea Anemone Peptide APETx2 Interacts with Acid-Sensing Ion Channel 3 and hERG Channels via Overlapping Pharmacophores

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Year: 2014
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/jm501400p
Authors: Jonas E. Jensen, Ben Cristofori-Armstrong, Raveendra Anangi, K. Johan Rosengren, Carus H. Y. Lau, Mehdi Mobli, Andreas Brust, Paul F. Alewood, Glenn F. King, Lachlan D. Rash
Institutions: The University of Queensland, Institute for Molecular Bioscience
Language: English

Topic: Ion channel regulation and function
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Health and Medical Research Council, Institute for Molecular Bioscience, University Of Queensland
Award: Development of new analgesics for the treatment of chronic pain
OpenAlex ID: W2071473924
FWCI: 2.322
Cites: 37
Cited by: 51
Related to: 10
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