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Design, Synthesis, and Biological Evaluation of Cytotoxic 11-Alkenylindenoisoquinoline Topoisomerase I Inhibitors and Indenoisoquinoline−Camptothecin Hybrids

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Year: 2003
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/jm0300476
Authors: Brian M. Fox, Xiangshu Xiao, Smitha Antony, Glenda Kohlhagen, Yves Pommier, Bart L. Staker, Lance Stewart, Mark Cushman
Institutions: National Institutes of Health, Purdue University West Lafayette, National Cancer Institute, Center for Cancer Research
Language: English

Topic: Cancer therapeutics and mechanisms
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Institutes of Health, National Cancer Institute
Awards: Anti-Cancer Drug Design Targeting Human Topoisomerase I, G256744984, G3029148, Novel Topoisomerase I Inhibitors, ANTICANCER COMPOUNDS DESIGNED TO POISON TOPOISOMERASE I, OPERATIONS &TECHNICAL SUPPORT, G6031895396, G6624597897, G8795886583, ANTICANCER DRUG DESIGN TARGETING HUMAN TOPOISOMERASE I
OpenAlex ID: W2071975065
FWCI: 1.608
Cites: 14
Cited by: 93
Related to: 10
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