Work

Measuring Protein Synthesis With SUnSET

Year: 2012

Type: review

Abstract: In Brief Protein synthesis rates commonly are measured using isotopic tracers to quantify the incorporation of a labeled amino acid into muscle proteins. Here we provide evidence supporting our hypothesis that the nonisotopic SUnSET technique is a valid and accurate method for the measurement of in vivo changes in protein synthesis at the whole-muscle and single–muscle fiber levels. SUnSET is a valid and accurate method for measuring protein synthesis at the whole-muscle and single–muscle fiber level.

Source: Exercise and Sport Sciences Reviews

DOI: 10.1097/jes.0b013e3182798a95

Authors: Craig A. Goodman, Troy A. Hornberger

Institution: University of Wisconsin–Madison

Language: English

Topic: Muscle metabolism and nutrition

Subfield: Nutrition and Dietetics

Field: Nursing

Domain: Health Sciences

Open Access status: green

Funder: National Institute of Arthritis and Musculoskeletal and Skin Diseases

Awards: G1190825394, Mechanotransduction and the Regulation of Skeletal Muscle Mass, Mechanotransduction and the Regulation of Skeletal Muscle Mass