Work

Discovery of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide (ABT-888) for the Treatment of Cancer

Year: 2008

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/jm801171j

Authors: Thomas D. Penning, Gui-Dong Zhu, Viraj B. Gandhi, Jianchun Gong, Xuesong Liu, Yan Shi, Vered Klinghofer, Eric F. Johnson, Cherrie K. Donawho, David J. Frost, Velitchka Bontcheva-Diaz, Jennifer J. Bouska, Donald J. Osterling, Amanda M. Olson, Kennan C. Marsh, Yan Luo, Vincent L. Giranda

Institution: Abbott (United States)

Language: English

Topic: PARP inhibition in cancer therapy

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W2072471623

FWCI: 11.05

Cites: 30

Cited by: 273

Related to: 10