Work

A demonstration of androgen and estrogen receptors in a human breast cancer using a new protamine sulfate assay

Year: 1976

Type: article

Abstract: Separate receptors for estrogen and androgen are demonstrated in cells from metastic human breast cancer. By criteria of binding affinity, number of binding sites, and specificity of the receptor for different steroids, the receptors are shown to be distinguishable. The protamine sulfate receptor assay technique employed allows both kinds of receptor to be quantified conveniently and reproducibly without interference by plasma steroid-binding components.

Source: Cancer

DOI: 10.1002/1097-0142(197608)38:2<868::aid-cncr2820380234>3.0.co;2-z

Authors: Marc Lippman, Karen Huff

Institution: National Cancer Institute

Language: English

Topic: Estrogen and related hormone effects

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2072678065

FWCI: 6.203

Cites: 29

Cited by: 61

Related to: 10