Work

Pleasant memories: remembering immune protection while forgetting about graft-versus-host disease

Year: 2003

Type: article

Abstract: Graft-versus-host disease (GVHD) represents a major cause of morbidity and mortality following conventional allogeneic hematopoietic stem cell transplantation (HSCT). A study in mice (see related article on pages 101–108) demonstrates that the selective administration of donor memory CD4(+) T cells results in immune reconstitution without GVHD, a result that, if translatable to humans, has important clinical implications for HSCT.

Source: Journal of Clinical Investigation

DOI: 10.1172/jci19095

Authors: Paul M. Sondel, Ilia N. Buhtoiarov, Kenneth DeSantes

Institutions: University of Wisconsin–Madison, University of Wisconsin Carbone Cancer Center

Language: English

Topic: Hematopoietic Stem Cell Transplantation

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2072856246

FWCI: 0.633

Cites: 17

Cited by: 17

Related to: 10