Year: 2008
Type: article
Abstract: Hazelnut (Corylus avellana) is one of the food sources that induce allergic reaction in a subpopulation of people with food allergy. The 11S legumin-like seed-storage protein from hazelnut has been identified as one of the major hazelnut allergens and named Cor a 9. In this study, Cor a 9 was extracted from hazelnut kernels using a high-salt solution and was purified by desalting out and FPLC to a highly purified state. Diffraction-quality single crystals were obtained using the hanging-drop vapour-diffusion method. Diffraction data were collected and a structure solution has been obtained by molecular-replacement calculations. Further refinement of the structure is currently in progress.
Authors: Feng Guo, Mahendra H. Kothary, Yang Wang, Xiaoping Yu, Andrew J. Howard, Tong-Jen Fu, Yu-Zhu Zhang
Language: English
Subfield: Immunology and Allergy
Field: Medicine
Domain: Health Sciences
SDG: Zero hunger
Open Access status: bronze
Awards: G2499065435, G7842164400
OpenAlex ID: W2072887475