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Location of Ribosomal DNA in the Human Chromosome Complement

Year: 1972

Type: article

Abstract: Hybridization of (3)H-labeled ribosomal RNA to human chromosomes on slides resulted in specific labeling of the satellite regions of chromosomes 13, 14, 15, 21, and 22, with an over-all efficiency of about 5%. Differences between D and G chromosomes, and between associated and unassociated satellites, were not significant. Labeling of all other parts of the preparations was nonspecific, and increased in the order: extrachromosomal regions < chromosome arms < centric regions.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.69.11.3394

Authors: A. S. Henderson, D. Warburton, K. C. Atwood

Institution: Columbia University

Language: English

Topic: Chromosomal and Genetic Variations

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W2072980043

FWCI: 11.97

Cites: 5

Cited by: 597

Related to: 10