Work

A mechanism for RNA splicing.

Year: 1980

Type: article

Abstract: The most abundant of the stable small nuclear RNAs of eukaryotic cells, U-1 small nuclear RNA, is exactly complementary to the consensus sequences at RNA splice sites. We propose that this RNA is the recognition component of the nuclear RNA splicing enzyme and forms base pairs with both ends of an intron so as to align them for cutting and splicing.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.77.4.1877

Authors: J Rogers, R Wall

Language: English

Topic: RNA Research and Splicing

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W2073105366

FWCI: 28.73

Cites: 43

Cited by: 535

Related to: 10