Work

Diindolylquinoxalines: Effective Indole-Based Receptors for Phosphate Anion

Year: 2006

Type: article

Abstract: The synthesis of a new series of 2,3-diindol-3'yl quinoxalines (DIQ), as well as a comparison of their anion recognition properties to those of our previously reported pyrrole based sensors, 2,3-dipyrrol-2'yl quinoxalines, is reported. To the best of our knowledge, this new DIQ system represents the first example of a free-standing indole-based small molecule receptor for which evidence of anion binding is available both in solution and in the solid-state. It also provides one of the few structurally characterized neutral receptor-dihydrogen phosphate complexes. This work thus serves to demonstrate the utility of indoles as an anion recognition motif.

Source: Journal of the American Chemical Society

DOI: 10.1021/ja067720b

Authors: Jonathan L. Sessler, Dong-Gyu Cho, Vincent Lynch

Institution: The University of Texas at Austin

Language: English

Topic: Molecular Sensors and Ion Detection

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funder: National Institute of General Medical Sciences

Awards: G1915311632, Oligopyrrole-based Anion Binding Agents