Work

Mouse models of colorectal cancer

Year: 2011

Type: review

Abstract: Colorectal cancer is one of the most common malignancies in the world. Many mouse models have been developed to evaluate features of colorectal cancer in humans. These can be grouped into genetically-engineered, chemically-induced, and inoculated models. However, none recapitulates all of the characteristics of human colorectal cancer. It is critical to use a specific mouse model to address a particular research question. Here, we review commonly used mouse models for human colorectal cancer.

Source: 癌症：英文版

DOI: 10.5732/cjc.011.10041

Authors: Yunguang Tong, Wancai Yang, H. Phillip Koeffler

Institutions: Cedars-Sinai Medical Center, University of Illinois Chicago

Language: English

Topic: Colorectal Cancer Treatments and Studies

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Cancer Institute