Estimation of DNA sequence divergence from comparison of restriction endonuclease digests
Year: 1977
Type: article
Abstract: An estimation of the DNA sequence divergence between defined DNA secquences of individuals or species may be made from comparison by gel electrophoresis of restriction endonuclease digests. This analysis is applicable to purified DNA sequence of moderate complexity (1-100 X 10(6) daltons) which have diverged by base substitution of 0.5 to 25% of nucleotides.
Source: Nucleic Acids Research
DOI: 10.1093/nar/4.5.1257
Author: William B. Upholt
Institution: University of Chicago
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2073909669