Work

Modification of Biomaterials with a Self‐Protein Inhibits the Macrophage Response

Year: 2014

Type: article

Abstract: A biomaterial inhibits the host immune response by displaying an endo-genously expressed immunomodulatory molecule, CD200. Immobilization of CD200 onto biomaterial surfaces effectively suppresses macrophage activation and reduces inflammatory response to subcutaneously implanted materials.

Source: Advanced Healthcare Materials

DOI: 10.1002/adhm.201300532

Authors: Yoon Kyung Kim, Richard Que, Szu‐Wen Wang, Wendy F. Liu

Institution: University of California, Irvine

Language: English

Topic: Polymer Surface Interaction Studies

Subfield: Surfaces, Coatings and Films

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Science Foundation, National Institutes of Health, National Institute of Dental and Craniofacial Research, Division of Materials Research