Interference with the Signaling Capacity of Cc Chemokine Receptor 5 Can Compromise Its Role as an HIV-1 Entry Coreceptor in Primary T Lymphocytes
Year: 1999
Type: review
Abstract: In this issue of The Journal of Experimental Medicine ([1][1]), Alfano et al. report the surprising results that pertussis toxin (PTX) as well as its cellular binding subunit, the B-oligomer, each blocked entry of monotropic (R5) strains of HIV-1 in primary T lymphocytes. Treatment of primary T
Authors: Ji Ming Wang, Joost J. Oppenheim
Language: English
Topic: HIV Research and Treatment
Subfield: Virology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W2074318090