1218 Salvage Robot-assisted Radical Prostatectomy for Recurrent Prostate Cancer: Safety and Feasibility
Year: 2013
Type: article
Study design: Observational Study
Abstract: You have accessJournal of UrologyProstate Cancer: Localized1 Apr 20131218 SALVAGE ROBOT-ASSISTED RADICAL PROSTATECTOMY FOR RECURRENT PROSTATE CANCER: SAFETY AND FEASIBILITY Andre Luis de Castro Abreu, Sanket Chauhan, Adrian Fairey, Ignacio Camacho, Alvin Goh, Andre Berger, Daniel Park, Mihir Desai, Vipul Patel, Inderbir Gill, and Monish Aron Andre Luis de Castro AbreuAndre Luis de Castro Abreu Los Angeles, CA More articles by this author , Sanket ChauhanSanket Chauhan Celebration, FL More articles by this author , Adrian FaireyAdrian Fairey Los Angeles, CA More articles by this author , Ignacio CamachoIgnacio Camacho Celebration, FL More articles by this author , Alvin GohAlvin Goh Los Angeles, CA More articles by this author , Andre BergerAndre Berger Los Angeles, CA More articles by this author , Daniel ParkDaniel Park Los Angeles, CA More articles by this author , Mihir DesaiMihir Desai Los Angeles, CA More articles by this author , Vipul PatelVipul Patel Celebration, FL More articles by this author , Inderbir GillInderbir Gill Los Angeles, CA More articles by this author , and Monish AronMonish Aron Los Angeles, CA More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2013.02.2572AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES The safety and feasibility of salvage robot-assisted radical prostatectomy (sRARP) for recurrent prostate cancer is unclear. Herein we report short-term cancer control, functional, and perioperative outcomes in a multi-institutional cohort. METHODS Between July 2007 and October 2011, 38 consecutive men underwent sRARP for recurrent prostate cancer at the University of Southern California (n=14) or Global Robotics Institute (n=24). Failed primary therapy was varied (external beam radiotherapy [EBRT; n=14]; interstitial brachytherapy [IBT; n=11]; EBRT + IBT [n=5]; high-intensity focused ultrasound [n=3]; cryoablation [n=3]; other [n=2]). The main outcomes were immediate biochemical failure (IBF), positive surgical margins (PSM), urinary continence and erectile function at 3 months, and complications within 90 days of surgery. Immediate biochemical failure was defined as a PSA > 0.2 ng/ml. Urinary continence was defined as the use of no pads and erectile function was defined as a SHIM score > 21. Complications were classified and graded using the Clavien system. RESULTS The median age was 68 years (50-83 years) and median preoperative PSA was 4.1 ng/ml (0.4-15.2 ng/ml). Preoperative biopsy Gleason score was ≤6 (n=7), 7 (n=18), and ≥8 (n=12). All procedures were completed without the need for open conversion. No patient experienced an intra-operative complication. Median estimated blood loss was 100 ml (30-300 ml) and operative time was 1.5 h (1-6h). Median length of hospital stay was 1 day (1-7 days). The median duration of urethral catheterization was 12 days (4-48 days). IBF occurred in 9 (29%) patients and PSM occurred in 7 (18%) patients. Urinary continence and erectile function occurred in 9 (34%) and 0 patients, respectively. One or more postoperative complications occurred in 12 (31%) patients. Low grade (I-II) and high grade (III-IV) complications occurred in 8 (21%) and 4 (10%) patients, respectively. No patient died. CONCLUSIONS Salvage robot-assisted radical prostatectomy is safe and feasible. Short-term cancer control and perioperative morbidity were acceptable. © 2013 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 189Issue 4SApril 2013Page: e499 Advertisement Copyright & Permissions© 2013 by American Urological Association Education and Research, Inc.MetricsAuthor Information Andre Luis de Castro Abreu Los Angeles, CA More articles by this author Sanket Chauhan Celebration, FL More articles by this author Adrian Fairey Los Angeles, CA More articles by this author Ignacio Camacho Celebration, FL More articles by this author Alvin Goh Los Angeles, CA More articles by this author Andre Berger Los Angeles, CA More articles by this author Daniel Park Los Angeles, CA More articles by this author Mihir Desai Los Angeles, CA More articles by this author Vipul Patel Celebration, FL More articles by this author Inderbir Gill Los Angeles, CA More articles by this author Monish Aron Los Angeles, CA More articles by this author Expand All Advertisement Advertisement Loading ...
Source: The Journal of Urology
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2074613639