Geometrically directed selective steroid hydroxylation with high turnover by a fluorinated artificial cytochrome P-450
Year: 1998
Type: article
Abstract: A metalloporphyrin has been synthesized carrying a beta-cyclodextrin group on tetrafluorophenyl rings at the four meso positions of the porphyrin. It performs the selective hydroxylation of an androstanediol derivative with complete positional selectivity and 187 turnovers.
Source: Tetrahedron Letters
Authors: Ronald Breslow, Bartolo Gabriele, Jerry Yang
Institution: Columbia University
Language: English
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Open Access status: hybrid
Estimated APC paid: $3,610
OpenAlex ID: W2074613919