Work

ZnS nanocrystals decorated single-walled carbon nanotube based chemiresistive label-free DNA sensor

Year: 2011

Type: article

Abstract: We fabricated ZnS nanocrystals decorated single-walled carbon nanotube (SWNT) based chemiresistive sensor for DNA. Since the charge transfer in the hybrid nanostructures is considered to be responsible for many of their unique properties, the role of ZnS nanocrystals toward its performance in DNA sensor was delineated. It was found that the free carboxyl groups surrounding the ZnS nanocrystals allowed large loading of single strand DNA (ssDNA) probe that provided an ease of hybridization with target complementary c-ssDNA resulting in large electron transfer to SWNT. Thus it provided a significant improvement in sensitivity toward c-ssDNA as compared to bare SWNT based DNA sensor.

Source: Applied Physics Letters

DOI: 10.1063/1.3529951

Authors: Rajesh, Basanta K. Das, Sira Srinives, Ashok Mulchandani

Institutions: University of California, Riverside, Council of Scientific and Industrial Research, CSIR National Physical Laboratory of India

Language: English

Topic: Advanced biosensing and bioanalysis techniques

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: National Science Foundation, National Institutes of Health, National Institute of Environmental Health Sciences

Awards: A HIGHLY SENSITIVE MICROCANTILEVER-BASED IMMUNOSENSOR ARRAY, Wearable Nanosensor Array for Real-Time Monitoring of Diesel and Gasoline Exhaust