Work

Transition Metal Photoredox Catalysis of Radical Thiol-Ene Reactions

Year: 2012

Type: article

Abstract: We describe the anti-Markovnikov hydrothiolation of olefins using visible-light-absorbing transition metal photocatalysts. The key thiyl radical intermediates are generated upon quenching of photoexcited Ru*(bpz)3(2) with a variety of thiols. The adducts of a wide variety of olefins and thiols are formed in excellent yield (73-99%).

Source: The Journal of Organic Chemistry

DOI: 10.1021/jo3020825

Authors: Elizabeth L. Tyson, Michael S. Ament, Tehshik P. Yoon

Institution: University of Wisconsin–Madison

Language: English

Topic: Radical Photochemical Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute of General Medical Sciences

Award: Visible Light Photocatalysis