Work

Lipid rafts and membrane traffic

Year: 2007

Type: review

Abstract: Membrane rafts are regions of increased lipid acyl chain order that differ in their lipid and protein composition from the surrounding membrane. By providing an additional level of compartmentalization they have been proposed to serve many functions in cellular signal transduction and trafficking. We will review their potential involvement in different forms of membrane traffic, explicitly excluding signalling, and discuss select aspects of the raft hypothesis in its current form.

Source: FEBS Letters

DOI: 10.1016/j.febslet.2007.03.019

Authors: Michael F. Hanzal-Bayer, John F. Hancock

Institutions: The University of Queensland, Institute for Molecular Bioscience

Language: English

Topic: Lipid Membrane Structure and Behavior

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funder: National Institute of General Medical Sciences

Award: Structure and Function of Plasma membrane Nanodomains