Year: 2010
Type: article
Abstract: Therefore, the preparation of chiral PNA monomers with high optical purity for PNA oligomers with high binding affinity to the complementary nucleic acids and the determi-nation of their optical purity have become essential features. However, the direct enantiomer separation of PNA monomers to determine the optical purity has not been reported, although some indirect analytical methods using HPLC, GC and NMR were developed.
Authors: Hu Huang, Goon-Ho Joe, Sung-Rok Choi, Su-Nam Kim, Yong-Tae Kim, Chwang-Siek Pak, Joon-Hee Hong, Won-Jae Lee
Institutions: Chosun University, Daejeon Technopark
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W2075341512