Work

Characterization of a gamma-carboxyglutamic acid-containing protein from bone.

Year: 1976

Type: article

Abstract: A gamma-carboxyglutamic acid-containing protein has been purified from the calcified tissues of several vertebrates. The presence of three-gamma-carboxyglutamic acid residues in the bovine protein was established by alkaline hydrolysis and amino acid analysis, a method based upon studies with synthetic gamma-carboxyglutamic acid. The identity of gamma-carboxyglutamic acid in the bovine protein was established by mass spectroscopy on the unknown amino acid isolated from alkaline hydrolysates.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.73.5.1447

Authors: P A Price, A A Otsuka, J W Poser, J Kristaponis, N Raman

Language: English

Topic: Bone and Dental Protein Studies

Subfield: Biochemistry

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W2075721622

FWCI: 6.344

Cites: 13

Cited by: 793

Related to: 10