Serum unmetabolized folic acid in a nationally representative sample of adults ≥60 years in the United States, 2001–2002
Year: 2012
Type: article
Study design: Observational Study
Abstract: Folic acid is a compound that does not occur naturally in food but is added as a fortificant and dietary supplement. When it is ingested it is converted into forms of reduced folate that are identical to those arising from ingestion of naturally occurring folate in foods; however, some folic acid may appear unmetabolized in the serum (1, 2). Very little is known about its metabolism and biological effects. Folic acid fortification increased dietary intakes of folic acid (3) and blood folate levels in the United States (4). Some (5-9) but not all (10-12) research suggests that high folic acid intakes may promote the growth of pre-existing cancers or malignant lesions.Keywords: folic acid; folate; NHANES; folic acid fortification(Published: 2 April 2012)Citation: Food & Nutrition Research 2012. 56 5616 - DOI: 10.3402/fnr.v56i0.5616
Source: Food & Nutrition Research
Institutions: National Institutes of Health, Office of Dietary Supplements, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Centers for Disease Control and Prevention, National Center for Health Statistics, National Center for Environmental Health, National Cancer Institute
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,103
OpenAlex ID: W2075947895