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Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors

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Year: 2008
Type: article
Source: Oncogene
DOI: 10.1038/onc.2008.49
Authors: L S Steelman, P M Navolanic, M L Sokolosky, J R Taylor, B D Lehmann, W H Chappell, S L Abrams, E W T Wong, K M Stadelman, D M Terrian, N R Leslie, A M Martelli, F Stivala, M Libra, R A Franklin, J A McCubrey
Institutions: East Carolina University, University of Dundee, University of Bologna, University of Catania
Language: English

Topic: PI3K/AKT/mTOR signaling in cancer
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute
Award: Ras/Raf & PI3K/Akt Induced Breast Cancer Drug Resistance
OpenAlex ID: W2076203883
FWCI: 4.547
Cites: 43
Cited by: 172
Related to: 10
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