Work

Neurodistribution of Androgen Receptor Immunoreactivity in the Male Frog, Rana esculenta

Year: 2005

Type: article

Abstract: Sexual behavior in vertebrates depends on the cyclic release of steroids and their binding to the brain receptors. Previously, we demonstrated the presence of specific binding of (3)H-testosterone and staining with PG-21 in the brain of the adult male frog, Rana esculenta. Here, we report our further receptor characterization using an anti-androgen receptor antiserum, PG-21, and the androgen site of action in frog brain. Nuclei, which contained cells labeled for the androgen receptor (AR), were mainly identified in the olfactory bulbs, preoptic-septal region, infundibulum, amygdala, thalamus, tectum, torus semicircularis, and medulla. The neuroanatomical AR staining appears similar to that in other lower vertebrates.

Source: Annals of the New York Academy of Sciences

DOI: 10.1196/annals.1327.054

Authors: G GUERRIERO, G S PRINS, L BIRCH, G CIARCIA

Institutions: University of Illinois Chicago, University of Naples Federico II

Language: English

Topic: Reproductive biology and impacts on aquatic species

Subfield: Physiology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funder: National Institute of Diabetes and Digestive and Kidney Diseases

Award: Development Estrogenization of the Rat Prostate Gland