Year: 2013
Type: article
Study design: Observational Study
Abstract: BACKGROUND: Heart rate variability (HRV) differs markedly by race, yet few studies have evaluated these relationships in women, and none have done so during sleep (sHRV). METHODS: We addressed these gaps by examining sHRV in women of African American, Chinese American, or European American origin or descent (mean [standard deviation] age = 51.2 [2.2] years). RESULTS: HRV during Stage 2 non-rapid eye movement (NREM) and rapid eye movement (REM) sleep differed significantly by race after adjusting for possible confounders. Normalized high-frequency HRV was significantly lower in European American compared with African American and Chinese American participants (European American NREM = 0.35 [0.01], REM = 0.23 [0.01]; African American NREM = 0.43 [0.02], REM = 0.29 [0.02]; Chinese American NREM = 0.47 [0.03], REM = 0.33 [0.02]; p values <.001). European Americans also exhibited higher low-to-high-frequency HRV ratios during sleep compared with African American and Chinese American women (European American NREM = 2.42 [1.07], REM = 5.05 [1.07]; African American NREM = 1.69 [1.09], REM = 3.51 [1.09]; Chinese American NREM = 1.35 [1.07], REM = 2.88 [1.13]; p values <.001). CONCLUSIONS: Race was robustly related to sHRV. Compared with women of African American or Chinese American origin or descent, European American women exhibited decreased vagally mediated control of the heart during sleep. Prospective data are needed to evaluate whether sHRV, including race differences, predicts cardiovascular disease.
Source: Psychosomatic Medicine
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funders: U.S. Department of Health and Human Services, Massachusetts General Hospital, Rush University, National Institutes of Health, University of California, Davis, National Institute on Aging, National Heart, Lung, and Blood Institute, National Institute of Nursing Research, National Center for Research Resources, Office of Research on Women's Health, National Center for Advancing Translational Sciences
Awards: G1078949291, G1334482291, G1395245948, Study of Women's Health Across the Nation (SWAN) V: UCLA Site, Study of Women's Health Across the Nation (SWAN) V: Chicago site, G1650445419, G1692154449, G1694870497, Study of Women's Health Across the Nation (SWAN): New Jersey, G2008899084, G2069832255, G2148195735, G2328791590, G240534699, G2490884996, G2701036747, G2853426343, G2886598935, G2899798242, Study of Women's Health Across the Nation (SWAN) V: Coordinating Center, University of Pittsburgh Clinical and Translational Science Institute, G3862244033, G4002206572, G4023110948, G4088562605, G4094362930, Study of Women's Health Across the Nation (SWAN) V: Central Laboratory, G4492651742, G4668657675, G4700637452, G4847607846, SWAN Sleep Study II: Pittsburgh, G5135050530, G5212787517, G5481793173, G5642491254, G6138161980, G6326023081, G6356525961, G6423459859, G6454223305, G6683184264, G6864660589, Sleep: A Novel Pathway Linking Major Depression and Cardiovascular Disease, Study of Women's Health Across the Nation (SWAN V): Michigan Site, G6881890559, G7076164640, G711645435, G7265740541, SWAN Sleep Study II - Michigan Center, G8334913947, Study of Women's Health Across the Nation(SWAN) V: Pittsburgh, SWAN Sleep Study II - Chicago (Rush) Site, G8711099106, G8762501422, G8801516908, G884570035, G8865318642, G9000000368, G9000052321, G9000210042, G9000300514, G9000352021, G9000354297, G988252460
OpenAlex ID: W2076746891