Work

MicroFootPrinter: a tool for phylogenetic footprinting in prokaryotic genomes

Year: 2006

Type: article

Abstract: Phylogenetic footprinting is a method for the discovery of regulatory elements in a set of homologous regulatory regions, usually collected from multiple species. It does so by identifying the most conserved motifs in those homologous regions. This note describes web software that has been designed specifically for this purpose in prokaryotic genomes, making use of the phylogenetic relationships among the homologous sequences in order to make more accurate predictions. The software is called MicroFootPrinter and is available at http://bio.cs.washington.edu/software.html.

Source: Nucleic Acids Research

DOI: 10.1093/nar/gkl069

Authors: S. Neph, M. Tompa

Institution: University of Washington

Language: English

Topic: Genomics and Phylogenetic Studies

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $3,992

Funders: National Science Foundation, University of Oxford, National Institutes of Health, National Human Genome Research Institute