Work

Measurement of frontal lobe volume on magnetic resonance imaging scans

Year: 1997

Type: article

Abstract: This article describes rules for measurement of the frontal lobe on thin SPGR (spoiled gradient recalled echo in steady state) MRI (magnetic resonance imaging) scans. Measurements were performed using a locally-developed software program that allows 3-dimensional reconstruction of images, 'painting' of landmarks on the surface of the brain, and reconstruction of 2-dimensional images in any plane with landmark 'paint' remaining on the surface of the brain. Excellent inter-rater reliability has been achieved for this method. The approach may be particularly useful for studies involving groups of patients whose brains are known to be dysmorphic and who may not, therefore, be appropriate for measurement methods that involve image warping or dependence on arbitrary landmarks for defining the posterior boundary of the frontal lobe.

Source: Psychiatry Research Neuroimaging

DOI: 10.1016/s0925-4927(97)00026-7

Authors: Elizabeth H. Aylward, Ann Augustine, Qiang Li, Patrick E. Barta, Godfrey D. Pearlson

Institutions: Johns Hopkins University, Johns Hopkins Medicine

Language: English

Topic: Fetal and Pediatric Neurological Disorders

Subfield: Pediatrics, Perinatology and Child Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,110