Work

TI nulling and contrast conditions with a 0.15 mmol/kg dosage of MultiHance as compared to the standard 0.2 mmol/kg gadolinium dosage in patients with myocardial infarcts

Year: 2009

Type: article

Abstract: It is known that utilizing the proper inversion time (TI) is essential when diagnosing myocardial infarction. Many factors play a role in acquiring optimal nulling of the myocardium. Recently, higher relaxivity contrast agents have been advocated for use in infarct imaging. Specifically, MultiHance ® (gadobenate dimeglumine) has higher relaxivities (r 1 and r 2, 9.7 1 and 12.5 1 ) compared to standard gadolinium (gadopentetate dimeglumine) (r 1 and r 2, 4.9 1 and 6.3 1 ). Will this higher relaxivity allow a lower dosage of contrast to be used to maintain a comparable TI null time compared to the conventional gadolinium dosage and how does it affect contrast?

Source: Journal of Cardiovascular Magnetic Resonance

DOI: 10.1186/1532-429x-11-s1-p189