Work

Reanalysis of Tyrannosaurus rex Mass Spectra

Year: 2009

Type: article

Abstract: Asara et al. reported the detection of collagen peptides in a 68-million-year-old Tyrannosaurus rex bone by shotgun proteomics. This finding has been called into question as a possible statistical artifact. We reanalyze Asara et al.'s tandem mass spectra using a different search engine and different statistical tools. Our reanalysis shows a sample containing common laboratory contaminants, soil bacteria, and bird-like hemoglobin and collagen.

Source: Journal of Proteome Research

DOI: 10.1021/pr900349r

Authors: Marshall Bern, Brett S. Phinney, David Goldberg

Institutions: Palo Alto Research Center, University of California, Davis

Language: Hebrew

Topic: Advanced Proteomics Techniques and Applications

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funder: National Institute of General Medical Sciences

Awards: Algorithms and Software for Difficult Proteomics Problems, G6450197189