Work

Tipping the scales early: probing the long-term effects of obesity

Year: 2012

Type: article

Abstract: Obesity has reached epidemic proportions in the United States, and obesity-related illnesses have become a leading preventable cause of death. Childhood obesity is also growing in frequency, and the impact of a lifetime spent in the overweight state is only beginning to emerge in the literature. In this issue of the JCI, Bumaschny et al. used a genetic mouse model to investigate the self-perpetuating nature of obesity and shed some light on why it can become increasingly difficult to lose weight over time.

Source: Journal of Clinical Investigation

DOI: 10.1172/jci66409

Authors: Chen Liu, Joel K. Elmquist

Institution: The University of Texas Southwestern Medical Center

Language: English

Topic: Regulation of Appetite and Obesity

Subfield: Endocrine and Autonomic Systems

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Hilda and Preston Davis Foundation, University of Texas Southwestern Medical Center, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases