Work

A Readily Available and User-Friendly Chiral Catalyst for Efficient Enantioselective Olefin Metathesis

Year: 2001

Type: article

Abstract: No glove box required! A new chiral catalyst for olefin metathesis is prepared from commercially available materials and is equally or more effective and selective than the previous systems. The new user-friendly catalyst can be prepared in situ (see scheme, Ar=aryl, Tf=trifluoromethanesulfonyl), isolation not needed, outside of a glove box, and delivers reactivity and enantioselectivity levels formerly available only through multiple catalysts.

Source: Angewandte Chemie International Edition

DOI: 10.1002/1521-3773(20010417)40:8<1452::aid-anie1452>3.0.co;2-g

Authors: Sarah L. Aeilts, Dustin R. Cefalo, Peter J. Bonitatebus, Jr., Jeffrey H. Houser, Amir H. Hoveyda, Richard R. Schrock

Institutions: Massachusetts Institute of Technology, Boston College

Language: English

Topic: Synthetic Organic Chemistry Methods

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

Funders: National Science Foundation, National Institutes of Health, National Institute of General Medical Sciences, Division of Chemistry

Awards: Catalytic Stereoselective Olefin Metathesis Reactions, New Methods in Stereoselective Synthesis, Multiple Metal-Carbon Bonds, Metallacycles, and Catalytic Reactions Involving Olefins and Acetylenes