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Photodynamic activity of viral nanoparticles conjugated with C60

Year: 2012

Type: article

Abstract: The development of viral nanoparticles (VNP) displaying multiple copies of the buckyball (C(60)) and their photodynamic activity is described. VNP-C(60) conjugates were assembled using click chemistry. Cell uptake and cell killing using white light therapy and a prostate cancer cell line is demonstrated.

Source: Chemical Communications

DOI: 10.1039/c2cc34695h

Authors: Amy M. Wen, Mary J. Ryan, Alice C. Yang, Kurt Breitenkamp, Jonathan K. Pokorski, Nicole F. Steinmetz

Institutions: Case Western Reserve University, University of Dayton, Scripps Research Institute

Language: English

Topic: Photodynamic Therapy Research Studies

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Biomedical Imaging and Bioengineering