Work

Expanding the Genetic Code of an Animal

Year: 2011

Type: article

Abstract: Genetic code expansion, for the site-specific incorporation of unnatural amino acids into proteins, is currently limited to cultured cells and unicellular organisms. Here we expand the genetic code of a multicellular animal, the nematode Caenorhabditis elegans.

Source: Journal of the American Chemical Society

DOI: 10.1021/ja2054034

Authors: Sebastian Greiss, Jason W. Chin

Institutions: MRC Laboratory of Molecular Biology, Medical Research Council

Language: English

Topic: RNA and protein synthesis mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $4,500

Funders: Louis-Jeantet Foundation, Medical Research Council