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Inactivation of Transmissible Spongiform Encephalopathy (Prion) Agents by Environ LpH

Year: 2004

Type: article

Abstract: Agents causing transmissible spongiform encephalopathy (TSE) diseases are resistant to inactivation by several conventional decontamination methods. Using an animal bioassay, we compared the TSE agent disinfectant efficacy of a commercially available product referred to alternatively as LpH-SE, LpH-AG, or LpH-st to that of a similarly named but differently formulated product, Environ LpH, which was found to be an effective TSE agent disinfectant in a previous study. Here, we found LpH-SE to be at least 10(4)-fold to 10(5)-fold less effective than Environ LpH.

Source: Journal of Virology

DOI: 10.1128/jvi.78.4.2164-2165.2004

Authors: Richard E. Race, Gregory J. Raymond

Institutions: National Institutes of Health, National Institute of Allergy and Infectious Diseases, Rocky Mountain Laboratories

Language: English

Topic: Prion Diseases and Protein Misfolding

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2080255530

FWCI: 1.068

Cites: 3

Cited by: 58

Related to: 10