Work

Temperature-Dependent Chemical Shift and Relaxation Times of 23Na in Na4HTm[DOTP]

Year: 2000

Type: editorial

Abstract: We describe the characterization of a (23)Na temperature-dependent chemical shift and relaxation rates in the complex, Na(4)HTm[DOTP]. This is the first characterization of a (23)Na temperature-dependent chemical shift in a nonmetallic sample. The (23)Na temperature-dependent chemical shift coefficient is approximately -0. 5 PPM/ degrees C for both an aqueous solution and a 6% agarose gel of this compound. This is 50 times the magnitude of the temperature-dependent chemical shift coefficient of water protons. The relaxation times, T(1), T(2f), and T(2s) increased by 0.1, 0.01, and 0.05 ms/ degrees C, respectively. Applications of these unique properties for designing an MRI technique for monitoring heat deposition in tissue and tissue phantoms are discussed.

Source: Journal of Magnetic Resonance

DOI: 10.1006/jmre.1999.2000

Authors: Erik M Shapiro, Arijitt Borthakur, Navin Bansal, John S Leigh, Ravinder Reddy

Institution: University of Pennsylvania

Language: English

Topic: Advanced NMR Techniques and Applications

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $3,500

Funders: National Institutes of Health, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Center for Research Resources