Work

Decreased Perfusion in Young Alcohol-Dependent Women as Compared With Age-Matched Controls

Year: 2007

Type: article

Abstract: AIM: To use the superior spatial resolution of magnetic resonance imaging (MRI) to examine differences in cerebral perfusion between young alcohol dependent and normal women. METHODS: Eight alcohol dependent women and 8 controls (all ages 18-25) received single-slice resting perfusion-weighted MRI (directly proportional to brain blood flow), with slices located above the corpus callosum. RESULTS: Alcohol-dependent women had decreased perfusion in prefrontal and left parietal regions. CONCLUSIONS: Reduced perfusion has not previously been reported in young, physically healthy alcohol dependent females, yet is consistent with previously reported decreased cerebral activity in alcohol dependence.

Source: The American Journal of Drug and Alcohol Abuse

DOI: 10.1080/00952990601082605

Authors: Camellia P. Clark, Gregory G. Brown, Lisa T. Eyler, Sean P. A. Drummond, Deborah R. Braun, Susan F. Tapert

Institutions: University of California San Diego, VA San Diego Healthcare System

Language: English

Topic: Substance Abuse Treatment and Outcomes

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institute on Alcohol Abuse and Alcoholism, National Institute of Mental Health, National Center for Research Resources