Work

Regioselective SN2 opening of α,β-ethylenic epoxides by RLi–BF3 combination

Year: 2000

Type: article

Abstract: Organolithium reagents effect a regioselective SN2 nucleophilic cleavage of α,β-ethylenic epoxides only when BF3·Et2O is added. The reaction works with a variety of RLi reagents and with cyclic as well as acyclic epoxides.

Source: Journal of the Chemical Society Perkin Transactions 1

DOI: 10.1039/b005472k

Authors: Alexandre Alexakis, Emmanuel Vrancken, Pierre Mangeney, Fabrice Chemla

Institutions: University of Geneva, Université Pierre-et-Marie-Curie

Language: English

Topic: Coordination Chemistry and Organometallics

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

OpenAlex ID: W2080987171

FWCI: 0.869

Cites: 24

Cited by: 20

Related to: 10