Work

An improved Huffman coding method for archiving text, images, and music characters in DNA

Year: 2009

Type: article

Abstract: An improved Huffman coding method for information storage in DNA is described. The method entails the utilization of modified unambiguous base assignment that enables efficient coding of characters. A plasmid-based library with efficient and reliable information retrieval and assembly with uniquely designed primers is described. We illustrate our approach by synthesis of DNA that encodes text, images, and music, which could easily be retrieved by DNA sequencing using the specific primers. The method is simple and lends itself to automated information retrieval.

Source: BioTechniques

DOI: 10.2144/000113218

Authors: Menachem Ailenberg, Ori D. Rotstein

Institutions: St. Michael's Hospital, University of Toronto, Keenan Research Centre for Biomedical Science

Language: English

Topic: DNA and Biological Computing

Subfield: Theoretical Computer Science

Field: Mathematics

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,415

Funder: Canadian Institutes of Health Research