Work

Photobilirubin: an early bilirubin photoproduct detected by absorbance difference spectroscopy.

Year: 1979

Type: article

Abstract: Absorption of light converts bilirubin-IXalpha in solution to a mixture of what are probably cis-trans geometric isomers. This reaction is much faster than other photochemical reactions of bilirubin and reaches photoequilibrium before losses due to photooxidation are significant. At room temperature in the dark in the presence of trifluoroacetic acid or iodine or simply on standing, the photoproducts revert to the natural isomer. They also revert under visible light. Their formation and reversion can be followed by chromatography on polyamide and by absorbance difference spectroscopy.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.76.1.29

Authors: D A Lightner, T A Wooldridge, A F McDonagh

Language: English

Topic: Neonatal Health and Biochemistry

Subfield: Pediatrics, Perinatology and Child Health

Field: Medicine

Domain: Health Sciences

Open Access status: green

OpenAlex ID: W2081878231

FWCI: 17.09

Cites: 9

Cited by: 77

Related to: 10